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个人信息
姓名:冯国强
学历:理学博士
职称:教授
E-mail:gf256@mail.ccnu.edu.cn
教育与研究经历
出生于1976年3月。现为滚球真人教授,博士生导师,化学滚球真人副院长。教育和研究经历:
1993年09月至1997年06月:湖北大学,获理学学士学位;
1997年09月至2000年06月:中国科滚球真人化学研究所,获理学硕士学位;
2000年09月至2003年06月:中国科滚球真人化学研究所,获理学博士学位;
2003年09月至2009年01月:先后在英国谢菲尔德大学(University of Sheffield)、英国剑桥大学(University of Cambridge)、英国利兹大学(University of Leeds)从事博士后研究;
2009年02月至今:滚球真人,教授、博士生导师;
研究领域与兴趣
1. 独立工作前主要从事生物催化与生物转化、金属模拟酶、动态组合化学等方面研究;
2. 独立工作后主要从事分子识别、小分子荧光探针、细胞和活体成像等方面的研究,研究方向主要涉及有机化学、化滚球真人物学、分析化学等交叉领域。
承担项目与课题信息
1. 主持国家自然科学基金面上基金(22077044),2021.01-2024.12;
2. 主持国家自然科学基金国际交流项目(22011530160),2020.07-2022.06;
3. 主持国家自然科学基金面上基金(21672080),2017.01-2020.12;
4. 主持国家自然科学基金面上基金(21472066),2015.01-2018.12;已结题;
5. 主持湖北省杰出青年基金(2014CFA042),2015.01-2017.12;已结题;
6. 主持国家自然科学基金面上基金(21172086),2012.01-2015.12,已结题;
7. 主持国家自然科学基金青年基金(20902033),2010.01-2012.12,已结题;
8. 参加国家自然科学基金重点项目(21032001),2011.01-2014.12,已结题。
学术成果
研究结果在J.Am.Chem.Soc.; Angew.Chem.Int.Ed.;Chem.Sci.;Anal.Chem.;ACS Sens.;Biosens. Bioelectron.;Sens.Actuators B Chem.等国际化学主流期刊上发表论文120余篇,先后有11篇论文入选ESI高被引论文,1篇论文入选ESI热点论文,h指数51。2018年获教育部自然科学奖二等奖(排名第三),2024年获湖北省自然科学奖三等奖(排名第三)。指导的滚球真人中有3名滚球真人的毕业论文入选湖北省优秀毕业论文,9名研究生获得国家奖学金,1名研究生获“周洪宇华大卓越人才奖”。
近期部分论文
[1] Siyu Jiang, Zhoupeng Zheng, Yijia Liu, Xiaodong Tan, and Guoqiang Feng*, Near-Infrared Fluorescent Lysosomal Viscosity Probe with Strong Solid Fluorescence for Rapid Imaging of Rheumatoid Arthritis, Analytical Chemistry, 2025, 97(10), 5661-5667. (中科院1区,Top期刊)
[2] Shiya Zhang, Shengyi Gong, Jiaxin Hong, Jinzheng Zhang, and Guoqiang Feng*, Dual-State Emissive Mitochondrial Viscosity Probe for Long-Term Imaging of Rheumatoid Arthritis, Analytical Chemistry, 2025, 97, 2318-2325. (中科院1区,Top期刊)
[3] Rongqing Luo, Li Xu, Jianmei Chen, Wenxuan Zhang, Shumin Feng*, Zhenpeng Qiua*, Yi Hong*, Guoqiang Feng, Near-Infrared Fluorescent Probe for Simultaneous Imaging Ferrous Ions and Viscosity of in a Mouse Model of Hepatocellular Carcinoma, Analytical Chemistry, 2025, 97, 1719-1728. (中科院1区,Top期刊)
[4] Qianhua Li, Zhoupeng Zhen, Yao Chen, Zhijie Li, Shumin Feng, and Guoqiang Feng*, Biotinylated Viscosity Sensitive Cell Membrane Probe for Targeted Imaging and Precise Visualization of Tumor Cells and Tumors, Analytical Chemistry, 2025, 97, 1627-1634. (中科院1区,Top期刊)
[5] Qianhua Li, Shumin Feng*, and Guoqiang Feng*, A cell membrane-targeted photosensitizer for cancer photodynamic therapy and dynamic ablation process tracking, Sensors and Actuators B: Chemical, 2025, 422, 136629. (中科院1区,Top期刊)
[6] Zhoupeng Zheng, Shengyi Gong, Qianhua Li, Shiya Zhang, and Guoqiang Feng*, Lipid Droplets-Targetable Fluorescent Probe for Ratiometric Imaging of NO in Gallstones Disease Models, Chinese Chemical Letters, 2025, 36(5), 110191. (中科院1区,Top期刊)
[7] Shengyi Gong, Guoqiang Feng*, Visible Light-Triggered NIR Ratiometric Fluorescent Metal-Free CO-Releasing Molecule for Self-Monitoring of CO Delivery and Effective Cancer Therapy, Chinese Chemical Letters, 2024. https://doi.org/10.1016/j.cclet.2024.110409. Available online 3 September 2024. (中科院1区,Top期刊)
[8] Xiaodong Tan, Jiaxin Hong, Siyu Jiang, Shiya Zhang, Yao Chen, and Guoqiang Feng*, Near-Infrared Fluorescent Probe Reveals Elevated Mitochondrial Viscosity During Acute Alcoholic Liver Injury, Analytical Chemistry, 2024, 96(37), 14860-14866. (中科院1区,Top期刊)
[9] Jinzheng Zhang, Shengyi Gong, Qianhua Li, Shiya Zhang, and Guoqiang Feng*, Lysosome-Targeted Polarity-Sensitive NIR Fluorescent Probe for Imaging Injured Lung and Liver in Diabetes, Analytical Chemistry, 2024, 96(34), 14053-14059. (中科院1区,Top期刊)
[10] Jianmei Chen, Rongqing Lou, Shuang Li, Jinping Shao, Li Xu*, Qiuyun You*, Shumin Feng*, Guoqiang Feng*, A novel NIR fluorescent probe for copper(II) imaging in Parkinson’s Disease mouse brain. Chemical Science 2024, 15(32), 13082-13089. (中科院1区,Top期刊)
[11] Shengyi Gong, Shumin Feng, Jinzheng Zhang, Qianhua Li, and Guoqiang Feng*, Red-emitting ratiometric fluorescent metal-free CO-releasing molecule for controllable CO delivery and efficient treatment of cutaneous wounds, Sensors and Actuators B: Chemical, 2024, 417, 136210. (中科院1区,Top期刊)
[12] Zhisheng Gui, Shengyi Gong, and Guoqiang Feng*, Constructing dual-state emissive fluorophores via Boc protection and discovering a high-fidelity imaging probe for lipid droplets, Analytical Chemistry, 2024, 96, 6724-6729. (中科院1区,Top期刊)
[13] Jinzheng Zhang, Shenyi Gong, Yijia Liu, Zhoupeng Zheng, and Guoqiang Feng*, Simultaneous detection of peroxynitrite and viscosity in diabetes by a dual response fluorescent probe, Sensors and Actuators B: Chemical, 2024, 406, 135432. (ESI高被引论文) (中科院1区,Top期刊)
[14] Zhoupeng Zheng, Shengyi Gong, Jinzheng Zhang, Yijia Liu, and Guoqiang Feng*, Golgi-targeted fluorescent probe for nitric oxide imaging in Parkinson’s disease models, Sensors and Actuators B: Chemical, 2023, 397, 134654. (中科院1区,Top期刊)
[15] Jiaxin Hong, Yijia Liu, Xiaodong Tan, Guoqiang Feng*, Engineering of a NIR fluorescent probe for high-fidelity tracking of lipid droplets in living cells and nonalcoholic fatty liver tissues, Biosensors and Bioelectronics, 2023, 240, 115646. (中科院1区,Top期刊)
[16] Wenlong Zhu, Qianhua Li, Shengyi Gong, and Guoqiang Feng*, Cell membrane targetable NIR fluorescent polarity probe for selective visualization of cancer cells and early tumor, Analytica Chimica Acta, 2023, 1278, 341748. (中科院2区,Top期刊)
[17] Siyu Jiang, Jiaxin Hong, Shengyi Gong, Qianhua Li, and Guoqiang Feng* Kidney-Targeted Near-Infrared Fluorescence Probe Reveals that SO2 Is a Biomarker for Cisplatin-Induced Acute Kidney Injury, Analytical Chemistry, 2023, 95, 12948-12955. (中科院1区,Top期刊)
[18] Qianhua Li, Wenlong Zhu, Shengyi Gong, Siyu Jiang, and Guoqiang Feng*, Selective Visualization of Tumor Cell Membranes and Tumors with a Viscosity-Sensitive Plasma Membrane Probe, Analytical Chemistry, 2023, 95, 7254-7261. (中科院1区,Top期刊)
[19] Jiaxin Hong, Xiaogang Guan, Yao Chen, Xiaodong Tan, Shiya Zhang, and Guoqiang Feng*, Mitochondrial Membrane Potential Independent Near-Infrared Mitochondrial Viscosity Probes for Real-Time Tracking Mitophagy, Analytical Chemistry, 2023, 95, 5687-5694. (中科院1区,Top期刊)
[20] Jiaxin Hong, Jinzheng Zhang, Qianhua Li, and Guoqiang Feng*, One Stone, Three Birds: A Smart Single Fluorescent Probe for Simultaneous and Discriminative Imaging of Lysosomes, Lipid Droplets, and Mitochondria, Analytical Chemistry 2023, 95, 2671–26791. (ESI高被引论文) (中科院1区,Top期刊)